Phenol genotoxicity
WebThe primary purpose of this chapter is to provide public health officials, physicians, toxicologists, and other interested individuals and groups with an overall perspective on the toxicology of pentachloro-phenol. It contains descriptions and evaluations of toxicological studies and epidemiological investigations and provides conclusions, where possible, on … WebPhenol and cresols are common toxic environmental pollutants. In this study, the micronucleus assay and the alkaline single cell gel electrophoresis (SCGE) technique have …
Phenol genotoxicity
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WebToxicity (IC 50 value, mM) of phenol and p -cresol to HT-29 and HCT 116 cells. In summary, these results were consistent with previous data reported in the bibliography that showed a direct toxic effect of phenol and p -cresol on human colonic epithelial cells in vitro. WebIn the pharmacokinetic study, PNP was well absorbed dermally, validating the negative dermal carcinogenicity assessment. These results indicate that PNP should be …
Webresearch article on phenol genotoxicity was retrieved, while no new publications on general toxicity were found. Concerning genotoxicity, phenol showed DNA-damaging activity in tests in vitro in yeast and mammalian cells. In studies in vivo with oral administration, … WebPhenol is a colorless or white solid when it is pure; however, it is usually sold and used as a liquid. (1) The odor threshold for phenol is 0.04 parts per million (ppm), with a strong very …
WebPhenol is considered to be an in-vivo somatic mutagen. It is assumed that there is a threshold for genotoxicity for oral exposure due to first-pass metabolism and … WebAllium cepa (A. cepa) has been recognized as a promising genetic model to detect the toxicity of industrial wastewater, contaminated soil, river water, nuclear contamination and even for those systems which are considered non toxic. A. cepa is distinguished as a low cost test, easy to handle and sensitive to both in vivo and in vitro models.
WebJul 1, 2005 · Phenol and cresols are common toxic environmental pollutants. In this study, the micronucleus assay and the alkaline single cell gel electrophoresis (SCGE) technique …
WebApr 12, 2024 · Genotoxicity, assessed by the Vicia-faba root cell, showed a significant decrease in micronucleus frequency of about 96% after fungal treatment. These results confirm the positive role of fungal treatment of OMWW to eliminate genotoxicity and their ability to improve the agronomic potential. Keywords: instant pot fiesta chickenWebPhenol has no mutagenic properties in bacterial gene mutation tests. There is evidence for gene and chromosome mutagenic effects in mammalian cells, mainly in the presence of … jio world bandraWebThe Panel considered a gavage developmental toxicity study and an oral two-generation reproduction toxicity study as the two most robust toxicity studies, and performed a … jio world centre bkc opening dateWebPhenol and cresols are common toxic environmental pollutants. In this study, the micronucleus assay and the alkaline single cell gel electrophoresis (SCGE) technique have … jio world christmasWebPhenol but not the other monitored metabolites was also positively correlated with MN frequency (P less than 0.03). Thus, our data show that the formation of genotoxic metabolites from BZ probably involves hydroxyl radicals and ttM as well as phenol are likely to be responsible for the clastogenic effect of benzene in vivo. Publication types instant pot field peas and snapsinstant pot figgy pudding recipeWebIntegrated Risk Information System US EPA jio world centre in mumbai\u0027s bkc