Cisplatin or carboplatin
WebHowever, the toxicity of carboplatin was smaller than that of cisplatin in proximal tubular epithelial cells that had been preincubated with AGEs. Yokoo et al reported that carboplatin is not transported by organic cation transporter and MATE1/SLC47A1; 29 thus, the toxicity of carboplatin was not affected by decreasing the expression of MATE1 ... WebDec 1, 2024 · Docetaxel maintenance therapy versus best supportive care after first-line chemotherapy with different dose docetaxel plus cisplatin for advanced non-small cell lung cancer (TFINE study, CTONG-0904): an open-label, randomized, phase III trial - PMC Back to Top Skip to main content An official website of the United States government
Cisplatin or carboplatin
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WebUsually, the combination includes a type of chemo drug called a platinum compound (usually cisplatin or carboplatin), and another type of chemo drug called a taxane, such as paclitaxel (Taxol ®) or docetaxel (Taxotere ® ). These drugs are usually given as an IV (put into a vein) every 3 to 4 weeks. WebFeb 28, 2024 · The EP regimen (etoposide plus cisplatin), in particular, is the most frequently used chemotherapy regimen for initial treatment.4Carboplatin is also frequently used clinically as a replacement of cisplatin to reduce vomiting, neurotoxicity, and nephrotoxicity, but similarly it increases the risk of myelosuppression.
WebHowever, the toxicity of carboplatin was smaller than that of cisplatin in proximal tubular epithelial cells that had been preincubated with AGEs. Yokoo et al reported that carboplatin is not transported by organic cation transporter and MATE1/SLC47A1; 29 thus, the … WebApr 16, 2024 · All four planned doses of cisplatin or carboplatin were received by 82.5% of the patients in the pembrolizumab-combination group and by 74.3% of those in the placebo-combination group; 76.5% and...
WebJul 1, 2000 · Carboplatin provides an improved therapeutic index compared to cisplatin, especially in terms of reduced nonhematologic toxicities. However, added hematologic toxicity may be problematic when combining carboplatin with other myelosuppressive chemotherapeutic agents.
WebSep 12, 2024 · While physicians may use cisplatin and carboplatin for lung or ovarian cancer, cisplatin is also used to treat bladder and testicular cancer. The ordinary dosage of carboplatin is up to three times higher than that of cisplatin in many cases, but the …
WebDec 4, 2024 · Comparison of cisplatin and carboplatin exposure on germ cell populations of the human foetal testis. Quantification of germ cell subpopulations in the human foetal testis 72 h (a–c) and 240 h (d–f) following exposure to vehicle (VEH), cisplatin (CIS; 0.5 … dynasty warriors 5 xlWebIncluded trials evaluated etoposide, mitomycin with vindesine or vinblastine, cisplatin or carboplatin with paclitaxel, docetaxel, gemcitabine, or cisplatin and carboplatin in combination with tirapazamine. Doses varied between trials. The median number of … dynasty warriors 5: xtreme legends pcWebDec 7, 2024 · In this study, we compared the efficacy and safety between the cisplatin plus etoposide (EP) and carboplatin plus etoposide (EC) regimens. Methods A total of 1305 patients with previously untreated ES-SCLC were included in this study. Data from five … dynasty warriors 5 xtreme legends gamefaqsWebApr 10, 2024 · Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, … dynasty warriors 6 cheat engineWebMay 29, 2024 · For the first 4 cycles, participants also received etoposide 100 mg/m 2 on days 1, 2, and 3 and the investigator’s choice of carboplatin area under the plasma drug concentration-time curve 5 or cisplatin 75 … dynasty warriors 5 zhang feiWebFor some tumors, cisplatin appears to be superior to carboplatin in terms of therapeutic effectiveness (germ cell tumors, bladder cancer, head and neck cancer), while for others, effectiveness is comparable (lung cancer, ovarian cancer). Toxicity profiles are distinctly different for the two analogu … dynasty warriors 6 cheat engine tableWebOct 14, 2024 · The key difference between carboplatin and cisplatin is that carboplatin shows less consistent survival advantages, whereas cisplatin shows more consistent survival advantages in meta-analyses of … dynasty warriors 5 zhang he